EFFECT OF JANUVIA (SITAGLIPTIN) ON OXIDATIVE STRESS IN OBESE TYPE 2 DIABETIC SUBJECTS

Obesity and diabetes are states of increased inflammation and can influence the free radicals and inflammatory markers (chemicals in the blood which increase due to inflammation in the body) and are also major risk factors for atherosclerotic disease. In this study we want to see the effect of sitagliptin on these markers. We believe that Sitagliptin may exert an anti-inflammatory effect in the human.

The purpose of this study is to determine if the addition of sitagliptin to diabetic patients will provide added benefit. We believe that sitagliptin provides these added benefits by suppressing free radicals (charged substances that cause damage to the body) and inflammation

Eligibility

You are being asked to participate in this study because you have been diagnosed with type 2 diabetes mellitus, are obese and are on oral medication for your diabetes

Reimbursement

$150-$250

Investigator

Paresh Dandona, MD

Contact Information

Name: Teekam Lohano
Phone: 716-887-5104
Email: tlohano@kaleidahealth.org